Parkinson's Disease is a form of accelerated aging. The shaking, the tremors, the cognitive decline, the imbalance of neurotransmitters, and many other conditions of Parkinson's, lead to declining efficiency and function in the body. Eventually declining efficiency and function result in degeneration, aging, disease, and breakdown. This leads to further decline in efficiency and function, which continues the cycle of declining health and further breakdown in the body. The great many problems of Parkinson's accelerate this entire process of declining efficiency and function.

Each particular problem of Parkinson's needs to be addressed and neutralized as a form of anti-aging. One of the major problems of Parkinson's is tremors and shakes. The muscle fiber is firing off unregulated and is out of control. There are several ideas to calm the nerves and the muscles.

The body needs sufficient energy in the form of ATP in order for muscle relaxation to occur. In Harper's Biochemistry, "if intracellular levels of ATP drop, ATP is not available to bind the S-1 head, actin does not disassociate and relaxation does not occur (Harper's Biochemistry, 25th Edition, Appleton & Lance, Stanford, Connecticut, 2000, Page 720.)" The body needs sufficient intracellular levels of ATP to help buffer some of the effects of the misfiring of muscle fiber in the forms of shakes and tremors. Without proper ATP levels, the muscles misfiring will not be able to relax.

ATP energy is produced inside cells at the sites called mitochondria. Mitochondria are the engines of the cells, producing energy in the form of ATP.

Dr. Bob was a MD internal medicine, orthomolecular doctor, MD psychiatrist, chiropractor, and healer 65 years. He was a diabetic who lived to 108 years with only 1 side effect 2 years before he passed away. Dr. Bob practiced a system of medicine called orthomolecular medicine.

The following ideas are orthomolecular methods to help relax muscle fiber and nerve stimulation. Orthomolecular medicine is a system of medicine that uses non-toxic, natural substances, in a wide range of dose, using mainly herbs and minerals/vitamins.

Dr. Bob's orthomolecular ideas:

1. Supplement a multivitamin and mineral. Dr. Bob recommended the brand Maxilife. All nutritional ideas need cofactors, which a multi provides.

2. Supplement a B-50, 3 times a day. B-1, B6, B3 and other B vitamins are involved in the production of energy in the mitochondria. The B vitamins start the energy process, they help control the buildup of waste products, they help regulate absorption into cell membranes, and other vital functions that help the mitochondria produce ATP.

3. Supplement CoQ10. CoQ10 supplies electrons in the energy cycle of the mitochondria. This is vital in producing ATP. There are different forms of CoQ10 and different potencies. The optimal dose has not yet been found in orthomolecular medicine, although 200-400 mg is a dose that is being considered by some doctors. CoQ10 probably has a toxic dose, so consult a nutritional expert such as an orthomolecular doctor, for the appropriate CoQ10 dose.

4. Supplement alpha lipoic acid 200 mg, 3 times a day. Alpha lipoic acid can help promote mitochondria cellular health, can help increase absorbability of nutrients important for the mitochondria, can help improve nerve conduction, which will help the mitochondria, and many other valuable functions of alpha lipoic acid at the mitochondria sites.

5. Supplement a total of 750 mg of no-flush hexanicotinate niacin, in divided doses, at the same time you use the B-50. Niacin is involved in increasing cell membrane permeability, which will help all the other nutrients.

6. Supplement ion-exchange whey protein concentrate. Whey supplies essential amino acids, building blocks of the body, and necessary to repair and rebuild muscle and nerves.

Additionally, in Harper's Biochemistry, "Calcium plays a key regulatory role," in the regulation of muscle contraction and relaxation. Proper levels of calcium are necessary to control muscle fiber. In the shaking type of tremors of Parkinson's, the nerve stimulation is erratic and can stimulate the parasympathetic and sympathetic nervous system. This can create intracellular imbalance, including unregulated calcium inside muscle cells.

The following orthomolecular ideas are to help promote proper calcium levels inside and outside cells, as well as reestablishing proper nerve conduction and nerve balance within cells.

1. Start at 1000 mg calcium supplementation a day, in divided doses. We recommend using calcium supplements that contain elemental calcium, the calcium found in your bones. Do not drink milk or eat chocolate around the time of calcium supplementation.

2. Start at 500 mg total magnesium supplementation each day. Supplement the calcium-magnesium at the same time, in a ratio of 2 parts calcium to 1 part magnesium.

3. Supplement vitamin B6 in the ratio of 3 parts magnesium to 1 part B6. Include the amounts of B6 in the B-50 and multivitamin and mineral.

4. Find your magnesium bowel tolerance. Most optimal amounts of supplements are not known. The body contains infinite wisdom. When you have too much magnesium, your body produces bowel movements to eliminate excess magnesium. Dr. Bob advised to supplement, ½ to 1-gram total of magnesium, each day. He recommended divided doses. He advised use optimal doses until bowel tolerance occurs (bowel movement immediately after using the supplement), afterwards use a dose slightly lower than bowel tolerance. For example, if you supplement magnesium in the AM and immediately afterwards have a bowel movement, then reduce your AM magnesium dose to slightly less than a dose that produces an immediate bowel movement. Do the same process with your magnesium dose in the PM. This is a basic guideline on finding an optimal magnesium dose, see an orthomolecular doctor or nutrition specialist before starting any of these ideas.

Special note - The stress of chronic disease often disrupts cellular balance, by increasing calcium inside cells. Supplementing calcium-magnesium in appropriate ratio helps to maintain cellular balance, by controlling parathyroid hormone (PTH). The parathyroid hormone (PTH) secretions maintain cellular balance by helping maintain appropriate levels of calcium in the bloodstream. "PTH secretion is inversely related to the ambient concentration of ionized calcium. Serum PTH declines in a rectilinear fashion in relation to serum calcium levels between 7.5 ml and 10.5 mg/dl. (Ref. Robert K. Murray, MD, Ph.D., Daryl K. Granmer, MD, Peter A. Mayes, Ph.D., D.Sc., Victor W. Fodwell, Ph.D., Harper's Biochemistry, twenty-fifth edition. Appleton & Lance, Stanford, Connecticut, 2000, page 570.)" This means levels of calcium in the bloodstream regulate PTH. The amount of PTH in the bloodstream helps regulate normal extra cellular fluid calcium. Magnesium is a cofactor in this cell regulation process.

Include all the above supplements at the same time. The misfiring of muscle fiber possibly indicates improper levels of calcium inside cells and depletion of ATP. The above orthomolecular methods can help balance calcium levels and help produce ATP.

Dr. Bob note - Many nutritional protocols involving the mitochondria include supplementing L-carnitine or acetyl-L-carnitine. L-carnitine can help transport fat to the mitochondria to be burned as energy, which is usually recommended to improve mitochondria function. However, in orthomolecular medicine, L-carnitine supplementation is a method also used to regenerate nerve velocity. Dr. Bob advised to be careful that supplementing L-carnitine does not lead to increasing shakes and tremors in Parkinson's. If you supplement L-carnitine and you have Parkinson's, observe carefully if your tremors and shakes increase. Perhaps in beginning stages of Parkinson's L-carnitine may not result in increased shakes and tremors. Dr. Bob advised to be cautious about acetyl-L-carnitine supplementation for Parkinson's.

Dr. Bob also included other orthomolecular methods to calm muscle fiber and nerves. His basic idea was to increase Vo2 Max. This would help maintain proper pH levels at the muscle fiber. From Harper's Biochemistry, "Fatigue of muscles during exercise is a phenomenon that almost everyone has experienced. What is the cause? The primary cause is accumulation in muscle tissue not of lactate (due to anaerobic glycolysis), but rather of protons. Increase of protons (decreased pH) can affect the function of muscles in a number of ways (page 733)." There will be other articles about Parkinson's on this web site describing ways to buffer the muscle cells to help maintain proper pH. Proper pH is a method that can help regulate muscle fiber and calm muscle cells.

In conclusion, there are many conditions of pathology associated with Parkinson's. There is no magic bullet to the many conditions that can occur. Each problem must be neutralized and balanced, to help slow down the accelerated aging of Parkinson's.


Note – In order for these anti-aging ideas to be successful, you must use supplements of the highest quality. Dr. Bob often said, "almost all supplement companies produce poor quality." You can consider the product page of this web site. Almost all the products met Dr. Bob’s approval. Since he passed away we have attempted to keep the same high standards.

WARNING:  DO NOT STOP ANY TREATMENT OR MEDICATION YOU CURRENTLY USE.  CONSULT WITH YOUR DOCTOR BEFORE STARTING THE USE OF SUPPLEMENTS. 

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The Food and Drug Administration has not evaluated any of the statements contained on this web site. The information contained in this article is not intended to diagnose, treat, cure or prevent any disease. Remember each person's body is different and will react differently to various herbal, vitamin and mineral supplements. Therefore, any supplementation must be administered on an individual basis. Use the information found on this web site as precisely that: Information. You and your doctor must make any final decisions. This information is not meant to replace any doctor and patient consultation. This information should in no way replace your personal physician's advice.