What is ostarine (MK2866)?
Ostarine, also known as ostabolic or MK2866, is a selective androgen receptor modulator (SARM) developed by GTX Pharmaceuticals. Ostarine was originally developed to prevent muscle loss in people suffering from muscle wasting conditions such as HIV and cancer.
The main difference between SARMS and steroids is that SARMS have a special affinity for certain tissues like muscle and bone, but not for other tissues like the prostate, liver, and brain. They also don’t convert into unwanted molecules that cause side effects, like DHT or estrogen. This makes side effects associated with steroid usage like gynecomastia, water retention, hair loss etc. impossible with SARM usage.
Ostarine (MK2866) will provide subtle yet consistent gains in muscle size and muscle strength. Most users will gain 5-10 pounds of muscle over an 8-12 week ostarine cycle. MK-2866 causes no water retention or bloat and is only minimally suppressive of natural testosterone production so the gains you make are lasting and will stay with you once the cycle is over. Some of the benefits of MK 2866 include:
- Increased lean mass
- Better strength
- More endurance
- Joint healing abilities
- Improved sense of mood
Athletes are using ostarine to maximize the results they get from their training. For example, UFC fighter Amanda Ribas received a two-year suspension after testing positive for MK2866.
Uses of ostarine
MK 2866 is a very versatile SARM that can be used for bulking, cutting or recomposition. It’s also beneficial to include in a post cycle therapy (PCT) after a steroid cycle since it’ll help block catabolism and prevent muscle loss.
MK-2866 is a very popular SARM to include in bulking cycles because it helps increase strength, improves recovery and promotes joint health. I recommend stacking ostarine with ligandrol (LGD4033) for bulking.
Ostarine is a very popular SARM to include in cutting cycles because it will preserve muscle when on a low calorie diet. I recommend stacking ostarine with cardarine (GW50516) for cutting.
MK 2866 is a favorite when recomping due to its nutrient portioning results. One of the most common SARMS cycles is the SARMS triple stack which is a combination of ostarine, andarine (S4) and cardarine (GW501516).
Post Cycle Therapy (PCT)
As a SARM, MK 2866 selectively binds to the androgen receptors in muscle tissues. It continues activating androgen receptors while the PCT drugs nolvadex and clomid bring natural testosterone production back to normal. This continued activation in the muscle causes no loss of muscle mass or strength during the PCT. In fact, some users even report an increase in strength during their PCT!
However, bloodwork shows that higher doses of MK-2866 (over 25mg/day) can cause some slight suppression so you won’t want to use an MK 2866 dosage greater then 25mg/day in your PCT.
The suppression really isn’t an issue though because when you use ostarine in conjunction with a SERM like nolvadex (tamoxifen) or clomid (clomiphene), the stimulation of the pituitary and hypothalamus from the nolvadex/clomid offsets any possible suppression from the ostarine. In other worse, nolvadex and clomid get your endogenous testosterone levels back to normal while MK2866 offers the benefits of increased androgen receptor activity.
Side effects, dosages and half life
The only side effect users will notice when using ostarine is a mild suppression of testosterone production. With a low dosage, the rate of suppression will be extremely minimal and it’s not a major concern. A mini PCT with a well formulated multi-ingredient natural testosterone booster such as HCGenerate ES from needtobuildmuscle.com will return testosterone levels back to normal once the ostarine cycle is finished. MK-2866 is not liver toxic and does not affect cholesterol levels, blood pressure, your kidneys or your prostate.
The recommended dosage of MK-2866 for both men and women is 25 milligrams (mg) per day for 8- 12 weeks. The half-life is 24 hours so a once per day dose is all that is needed. It does not matter if you take ostarine on an empty stomach or with food. Also, since it is not a stimulant, taking it near bedtime will not affect sleep in any way.
Ostarine bulking cycle
|Week||Ostarine (MK2866)||Ligandrol (LGD4033)||HCGenerate ES||Clomid|
Ostarine cutting cycle
|Week||Ostarine (MK2866)||Cardarine (GW501516)||HCGenerate ES|
Ostarine recomposition cycle
|Week||Ostarine (MK2866)||Cardarine (GW501516)||Andarine
|1||25mg/day||20mg/day||50mg/day (25mg AM 25mg PM)|
|2||25mg/day||20mg/day||50mg/day (25mg AM 25mg PM)|
|3||25mg/day||20mg/day||50mg/day (25mg AM 25mg PM)|
|4||25mg/day||20mg/day||50mg/day (25mg AM 25mg PM)|
|5||25mg/day||20mg/day||50mg/day (25mg AM 25mg PM)|
|6||25mg/day||20mg/day||50mg/day (25mg AM 25mg PM)|
|7||25mg/day||20mg/day||50mg/day (25mg AM 25mg PM)|
|8||25mg/day||20mg/day||50mg/day (25mg AM 25mg PM)|
Post cycle therapy (PCT) lay out
|Week||Aromasin||HCGenerate ES||N2guard||Ostarine (MK2866)||Cardarine (GW501516)||Clomid||Nolvadex|
|1||12.5mg/ every other day||5 tablets/day||7 capsules/day||25mg/day||20mg/day|
|2||12.5mg/ every other day||5 tablets/day||7 capsules/day||25mg/day||20mg/day|
|3||5 tablets/day||7 capsules/day||25mg/day||20mg/day||50mg/ day||20mg
|4||5 tablets/day||7 capsules/day||25mg/day||20mg/day||50mg/ day||20mg
|5||7 capsules/day||25mg/day||20mg/day||25mg/ day||10mg
|6||7 capsules/day||25mg/day||20mg/day||25mg/ day||10mg
|7||7 capsules/day||25mg/day||20mg/day||25mg/ day||10mg
|8||7 capsules/day||25mg/day||20mg/day||25mg/ day||10mg
Where to buy ostarine?
SARMs1 is the only sarms provider we will recommend at this moment. Their products were examined and found to be of over 99% purity.